The SERPINA5 was strongly correlated with tau tangle progression in the hippocampus and cortex.
Article Correctness Is Author's Responsibility: Light Up Your Mind: A Novel Light-Based Treatment for Neurodegenerative Diseases
Light therapy which consists of exposure to both controlled natural light and artificial lighting may be a new tool in the treatment of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease.
Article Correctness Is Author's Responsibility: Gene That Could Help Prevent or Delay Onset of Alzheimer’s Disease Identified
Boosting the expression of the ABCC1 gene may not only reduce amyloid plaques in the brain, it might also delay the onset of Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Some Alzheimer’s Plaques May Be Protective, Not Destructive
Microglia creates dense-core plaques which help to clear away more wispy plaques from neurons, preventing cell death. Findings suggest the dense-core plaques play a defensive role in protecting the brain from the ravages of neurodegenerative diseases, …
Article Correctness Is Author's Responsibility: Imbalance in Gum Bacteria Linked to Alzheimer’s Disease Biomarker
An increase in bad gum bacteria and a decrease in good bacteria is associated with amyloid-beta in cerebral spinal fluid samples of older adults. The findings add to the growing body of evidence linking periodontal disease to the development of Alzheim…
Treating Sleep Apnea May Reduce Dementia Risk
People with sleep apnea who were exposed to positive airway pressure therapy had a reduced risk of being diagnosed with dementia.
Article Correctness Is Author's Responsibility: Fighting Dementia With Play
A newly developed play therapy platform is helping older adults with dementia improve a range of flagging cognitive skills from concentration to memory.
Article Correctness Is Author's Responsibility: Aluminum Is Intricately Associated With the Neuropathology of Familial Alzheimer’s Disease
Study reveals aluminum is co-located with the tau protein in people with familial Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Unusual Mechanism in Rare Mutation Associated With Alzheimer’s Uncovered
The S198P mutation causes APP to fold more quickly, allowing amyloid-beta peptides to produce from mature APP at a more rapid rate than from APP that does not contain the genetic mutation. The findings shed new light on genetic mutations associated wit…
Article Correctness Is Author's Responsibility: Thirteen New Alzheimer’s Genes Identified
A new whole-genome sequencing study has revealed thirteen novel genes associated with Alzheimer’s disease. Researchers also found a new link between Alzheimer’s and synaptic function.
Article Correctness Is Author's Responsibility: Experimental Antibodies for Parkinson’s and Alzheimer’s May Cause Harmful Inflammation
A new study reveals some experimental antibody treatments for neurodegenerative disorders increase neuroinflammation. The effect was seen in human microglia, not mouse microglia. This may explain why mouse studies have shown these treatments to be effe…
Article Correctness Is Author's Responsibility: Common Alzheimer’s Treatment Linked to Slower Cognitive Decline
Cholinesterase inhibitors such as galantamine, donepezil, and rivastigmine, appear to generate persistent cognitive benefits, and increased longevity for up to five years in Alzheimer’s patients.
Article Correctness Is Author's Responsibility: Women Accumulate Alzheimer’s-Related Protein Faster
Study reports tau accumulation in the temporal lobe was 75% higher in women than men.
Article Correctness Is Author's Responsibility: Repurposed Drug Improves Cognition in Alzheimer’s Patients
Sargramostim, a medication that boosts white blood cells following cancer treatment, appears to improve memory and cognition in people with mild-to-moderate Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Midlife Loneliness Is a Risk Factor for Dementia and Alzheimer’s Disease
Those who report feeling consistently lonely and socially isolated between the ages of 45 and 64 have an increased risk of developing dementia later in life. However, the risk can be reversed if people embark on activities to expand their social lives …
Article Correctness Is Author's Responsibility: Exercise Boosts Blood Flow to the Brain
Exercise helps increase blood flow to the brain in older adults with mild memory loss.
Article Correctness Is Author's Responsibility: Eating Processed Meat Could Increase Dementia Risk
Consumption of 25g of processed meats per day, the equivalent to one slice of bacon, was associated with a 44% increased risk of developing Alzheimer’s. However, those who ate 50g of unprocessed red meats, such as beef or pork, per day had a 19% decrea…
Article Correctness Is Author's Responsibility: Identifying Cells to Better Understand Healthy and Diseased Behavior
Using a range of tools from machine learning to graphical models, researchers have discovered a new way to identify cells and explore the mechanisms behind neurodegenerative diseases.
Article Correctness Is Author's Responsibility: Gene Therapy Using ‘Zinc Fingers’ May Help Treat Alzheimer’s Disease
A new genetic engineering strategy significantly reduces levels of tau in animal models of Alzheimer’s disease. The treatment, which involves a single injection, appears to have long-last effects.
Article Correctness Is Author's Responsibility: Animal Model Opens Way to Test Alzheimer’s Disease Therapies
Using rhesus macaques, researchers have developed a new model of early-stage Alzheimer’s disease.
