APOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer’s disease and slow cognitive decline.
Article Correctness Is Author's Responsibility: Drug Target Could Fight Parkinson’s and Alzheimer’s Disease
The SARM1 protein triggers a cascade of degeneration associated with Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Researchers hope new drugs can be developed to directly target this protein to fight neurodegeneration.
Article Correctness Is Author's Responsibility: Evolution Drives Autism and Other Conditions to Occur Much More Frequently in Boys
Hereditary forces that have evolved over millions of years favor mate selection and reproduction in the early years of male sexual maturity at the expense of longer-term well-being. This may explain why females tend to live longer and are less vulnerab…
Article Correctness Is Author's Responsibility: A Genetic Patch to Prevent Hereditary Deafness
A newly developed “genetic patch” can eliminate problematic hearing cells in those with DFNA9, a hereditary form of deafness.
Article Correctness Is Author's Responsibility: Dozens of Genes That Block Regeneration of Neurons
Study identifies 40 genes in mice that actively suppress axon regeneration in the central nervous system.
Article Correctness Is Author's Responsibility: Addressing a Complex World of Pain in a Single Gene Difference
Researchers say it is essential to analyze individual influences to better understand disparities in treatment and personal experience of sickle cell anemia.
Article Correctness Is Author's Responsibility: Individualized Brain Cell Grafts Reverse Parkinson’s Symptoms
Grafting neurons derived from a monkey’s own stem cells reversed the debilitating and mental health symptoms associated with Parkinson’s disease. The treatment shows promise for alleviating the symptoms of Parkinson’s in humans.
Article Correctness Is Author's Responsibility: A New Theory for How Memories Are Stored in the Brain
A new theory of memory visualizes the brain as an organic super-computer that runs complex binary code with neurons acting like mechanical computers. The theory is based on the discovery of the protein molecule, talin, which contains switch-like domain…
Article Correctness Is Author's Responsibility: Differences Related to Sexual Orientation Found in the Brain
A new neuroimaging study reveals brain patterns that differentiate between men and women are less pronounced in non-heterosexual people. The differences occurred primarily in sensory processing areas of the brain, in particular areas associated with vi…
Article Correctness Is Author's Responsibility: Genetic Treatment Extends Fruit Fly Lifespan and Prevents Alzheimer’s Damage
Modifying the levels of two different proteins active in two different brain cells extended the life of fruit flies by 7-9%. The treatment also reduced the buildup of Alzheimer’s related amyloid plaques within the brain.
Article Correctness Is Author's Responsibility: Reactivating Aging Stem Cells in the Brain
Increasing lamin B1 levels in aging mice resulted in neural stem cell division and an increase in the number of new neurons.
Article Correctness Is Author's Responsibility: Heart Problems Alter Gene Activity in the Hippocampus
Cardiovascular problems can alter gene activity in the hippocampus, increasing the risk for cognitive decline and memory deficits, a new study reports.
Article Correctness Is Author's Responsibility: The Impact of Patient Sex on Treatment Strategies for Spinal Cord Injuries
Both the ApoE genotype and the sex of the mouse impacted the manner in which the animals with spinal cord injury responded to hypoxia treatment. Females with the ApoE e4 gene had a negative response to intermittent hypoxia.
Article Correctness Is Author's Responsibility: Two New Genes Linked to Alzheimer’s Disease Discovered
A new study of gene expression in the hippocampus has unveiled two new genes potentially implicated in Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Gut Health and Mood Genetically Entwined
Researchers have identified a genetic link between depression and an increased risk of developing stomach ulcers.
Article Correctness Is Author's Responsibility: Uncovering the Molecular Mechanism Behind Synapse Loss in Alzheimer’s Disease
Over-expression of the synaptic protein RAPGEF2 drives synaptic loss associated with Alzheimer’s disease.
Article Correctness Is Author's Responsibility: Pain Perception Could Help Diagnose Alzheimer’s Before Symptoms Occur
Altered pain perception could be a new biomarker to assess late-onset Alzheimer’s risk in cognitively healthy individuals with the AopE4 gene before symptoms occur.
Article Correctness Is Author's Responsibility: Basic Cell Health Systems Wear Down in Huntington’s Disease
Huntington’s disease may progress to advanced stages as a result of degradation of the cells’ health maintenance system than due to the increased disease pathology itself.
Article Correctness Is Author's Responsibility: A Sleep Disorder Associated With Shift Work May Affect Gene Function
Study sheds light on DNA methylation related to sleep deprivation in those with shift-work disorder.
Article Correctness Is Author's Responsibility: ‘Mini Brain’ Organoids Grown in Lab Mature Much Like Infant Brains
Brain organoids, or mini-brains, created from human stem cells appear to develop in much the same way as a human brain. The organoids follow an internal clock that guides their maturation in sync with the timeline for human brain development.
